Takahashi, Yutaka

Associate Professor

Division of Diabetes and Endocrinology,

Department of Internal Medicine, Kobe University Graduate School of Medicine


1988: M.D., Kobe University

1996: Ph.D., (Doctor of Medicine), Kobe University Graduate School of Medicine

Thesis: Short stature caused by a mutant growth hormone (NEJM 1996)

Professional training:

1988: Junior resident at Internal Medicine in Kobe University Hospital

1991-1995: Graduate School of medicine, Kobe University

1999-2002: Postdoctoral fellow at Biochemistry Department, St. Jude Children’s Research Hospital (Prof. James Ihle: Analysis of hormone and cytokine signaling using genetic approach)

2006-2007: The chief at Division of Endocrinology/Metabolism at Kobe University Hospital

2014-present: Associate Professor at Division of Diabetes and Endocrinology Department of Internal Medicine, Kobe University Graduate Scholl of Medicine


The Endocrine Society: Member

The GRS-IGF Society: Member

The Pituitary Society: Member, the Corporate Liaison Committee

The Japan Endocrine Society: Director

The Japanese Society for Hypothalamic and Pituitary Disease: Director

The Japan Neuroendocrine Society: Director

Awards and Honors:

2012: The 6th GRS-IGF International meeting, plenary speaker

2018: The 18th International Congress of Endocrinology, plenary speaker
“Pituitary autoimmunity”

Research interest:

  1. GH and IGF-I
  2. Pathophysiology of pituitary diseases especially acromegaly and hypophysitis

He has established a novel clinical entity named “Anti-PIT-1 antibody syndrome”, a specific form of hypophysitis and elucidated the underlying mechanisms (JCI 2011, JCEM 2014, Sci Rep 2017, ICE 2018; plenary lecture). He also has reported regarding the pathophysiology and underlying mechanisms of hypophysitis including immune therapy-induced hypophysitis (EJE 2013, Pituitary 2015, 2019, J Endocri Soc 2018).